Duke Cancer Institute
#NEWS: A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine.
“Polioviruses have several advantages for generating antigen-specific CD8 T-cells as a potential cancer vaccine vector,” said senior author Matthias Gromeier, M.D., who developed the poliovirus-based therapy as a member of Duke’s Preston Robert Tisch Brain Tumor Center.
Gromeier said the vaccine approach continues to be tested with the goal of initiating a phase 1 clinical trial. Duke Children's #TheFutureOfCancerCareNow #ChangingTheRulesOnCancer
Full news release: https://corporate.dukehealth.org/news-listing/poliovirus-therapy-shows-potential-cancer-vaccine-lab-studies