Janelia Research Campus

Janelia Research Campus Janelia is a pioneering research center where scientists from many disciplines gather to collaborate on some of science's most challenging problems.
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Janelia scientists are working on discovering the basic rules and mechanisms of the brain's information-processing system and developing optical, biological, and computational technologies for creating and interpreting biological images.

Janelia scientists are working on discovering the basic rules and mechanisms of the brain's information-processing system and developing optical, biological, and computational technologies for creating and interpreting biological images.

Operating as usual

06/17/2021
Preview | Narry Kim defines miRNA

Wondering what short single-stranded #microRNA molecules are all about? 🤔

🎥 Then watch Narry Kim's #GlobalLifeSci lecture on how her team at the Institute for Basic Science is defining #miRNA and observing its important regulatory functions: https://bit.ly/3iPuFjQ

Our return to the Janelia Research Campus and the impromptu conversations that spark discovery was featured by NPR.“This...
06/14/2021
It's Personal: Zoom'd Out Workplace Ready For Face-To-Face Conversations To Return

Our return to the Janelia Research Campus and the impromptu conversations that spark discovery was featured by NPR.

“This building — it's been socially engineered so that you do have those kinds of collisions,” said Vivek Jayaraman, head of Mechanistic Cognitive Neuroscience at Janelia.

Before the pandemic, the Janelia Research Campus was a hive of collaboration. Now, as researchers return to their offices and labs, they're eager to restore the connections lost this past year.

Watch the full replay of our #GlobalLifeSci talks on Non-coding RNAs and Epigenetics—moderated by EMBL Director General ...
06/08/2021
Non-coding RNAs and Epigenetics

Watch the full replay of our #GlobalLifeSci talks on Non-coding RNAs and Epigenetics—moderated by EMBL Director General Edith Heard.

#ncRNA #epigenetics

Click "Show More" to see the full schedule of speakers and links to individual talks.Each month, Life Science Across the Globe highlights scientific and soci...

TOMORROW: Join us for a discussion and Q&A about Non-coding RNAs and Epigenetics at 9am ET. EMBL’s Edith Heard—recent WH...
06/01/2021

TOMORROW: Join us for a discussion and Q&A about Non-coding RNAs and Epigenetics at 9am ET. EMBL’s Edith Heard—recent WHO Science Council appointee—moderates our global panel hosted by Tsinghua-Peking Center for Life Sciences.

Event link: http://bit.ly/LSAGsems

#ncRNA #epigenetics #GlobalLifeSci

Don’t miss our next #GlobalLifeSci event “Non-coding RNAs and Epigenetics” with Thomas Cech, Xiaohua Shen, Narry Kim, an...
05/29/2021

Don’t miss our next #GlobalLifeSci event “Non-coding RNAs and Epigenetics” with Thomas Cech, Xiaohua Shen, Narry Kim, and moderator Edith Heard—Join us June 2 at 9am ET: http://bit.ly/LSAGsems

#ncRNA #epigenetics

National Centre for Biological Sciences - NCBS | MRC Laboratory of Molecular Biology

Join Nobel Prize winner Thomas Cech, Xiaohua Shen of Tsinghua University, and Narry Kim of Seoul National University for...
05/27/2021

Join Nobel Prize winner Thomas Cech, Xiaohua Shen of Tsinghua University, and Narry Kim of Seoul National University for a panel discussion and Q&A on Non-coding RNAs and Epigenetics. Moderated by EMBL Director General Edith Heard.

June 2 at 9am ET: https://bit.ly/LSAGcalendar

#ncRNA #epigenetics #GlobalLifeSci

MRC Laboratory of Molecular Biology | National Centre for Biological Sciences - NCBS | Peking University

Our monthly event series continues with an exciting panel discussion on Non-coding RNAs and Epigenetics—moderated by EMB...
05/25/2021

Our monthly event series continues with an exciting panel discussion on Non-coding RNAs and Epigenetics—moderated by EMBL Director General Edith Heard. Join us June 2 at 9am ET: https://bit.ly/3vlfT7I

#ncRNA #epigenetics #GlobalLifeSci

Our monthly event series continues with an exciting panel discussion on Non-coding RNAs and Epigenetics—moderated by EMBL Director General Edith Heard. Join us June 2 at 9am ET: https://bit.ly/3vlfT7I

#ncRNA #epigenetics #GlobalLifeSci

“We’ve got to start critiquing what we teach, how we teach, and who teaches it.”The University of Cape Town featured the...
05/24/2021

“We’ve got to start critiquing what we teach, how we teach, and who teaches it.”

The University of Cape Town featured the words of Vice-Chancellor Mamokgethi Phakeng during our May speaker event: “Inclusion of Underrepresented Populations in Science.” #GlobalLifeSci

https://www.news.uct.ac.za/article/-2021-05-21-as-much-as-education-changes-lives-lives-should-change-education

“We’ve got to start critiquing what we teach, how we teach, and who teaches it.”

The University of Cape Town featured the words of Vice-Chancellor Mamokgethi Phakeng during our May speaker event: “Inclusion of Underrepresented Populations in Science.” #GlobalLifeSci

https://www.news.uct.ac.za/article/-2021-05-21-as-much-as-education-changes-lives-lives-should-change-education

Join us on Wednesday, May 5 at 9 am. ET for the relaunch of Life Science Across the Globe! Janelia has teamed up with 7 ...
05/04/2021
Life Science Across the Globe

Join us on Wednesday, May 5 at 9 am. ET for the relaunch of Life Science Across the Globe! Janelia has teamed up with 7 other life sciences institutes on 5 continents to develop this monthly online event series, where leading scholars from around the world come together to discuss the most exciting advances in science and society. All events are free and open to anyone, anywhere.

Tomorrow’s event is “Inclusion of Underrepresented Populations in Science,” moderated by Kenny Gibbs from National Institute of General Medical Sciences. Speakers include Freeman Hrabowski and Michael Summers from UMBC, Mamokgethi Phakeng from University of Cape Town, Ramakrishna Ramaswamy from IIT Delhi, and Sonajharia Minz from Sido Kanhu Murmu University.

Special thanks to our partners, Cold Spring Harbor Laboratory, European Molecular Biology Laboratory - EMBL, MRC Laboratory of Molecular Biology, National Centre for Biological Sciences - NCBS , Instituto Ifibyne, and the UCT Institute of Infectious Disease and Molecular Medicine. Learn more, and sign up to attend, at lifescienceacrosstheglobe.org.

A virtual seminar series that brings together scientists and scholars around the world

ICYMI: Newly identified proteins in aphid saliva can reprogram plant development, coaxing witch hazel trees into produci...
03/12/2021
Here’s How Insects Coax Plants into Making Galls | Janelia Research Campus

ICYMI: Newly identified proteins in aphid saliva can reprogram plant development, coaxing witch hazel trees into producing a cone-shaped shelter for aphids rather than normal leaf tissue.

Howard Hughes Medical Institute (HHMI) Janelia Research Campus group leader David Stern and his colleagues have identified proteins in aphid saliva that can alter plant development. These proteins drive abnormal growths called galls, which give insects a protected place to feed and reproduce.

Igor Siwanowicz has been awarded the Royal Photographic Society's Scientific Imaging Award "for his macrophotography ima...
10/26/2020

Igor Siwanowicz has been awarded the Royal Photographic Society's Scientific Imaging Award "for his macrophotography images that accentuate the beauty and intricacies of natural forms." And his colorful microscope image of a snail tongue, shown here, recently won third place in the Nikon Small World photomicrography competition. Congratulations, Igor!

Learn more about the Scientific Imaging Award (and read a magazine feature about Igor's work) here: https://rps.org/about/awards
And see the complete gallery of Nikon Small World winners here: https://www.nikonsmallworld.com/galleries/2020-photomicrography-competition

10/14/2020
Dr. Angela Rasmussen: Demystifying COVID-19. The Science of SARS-CoV2 Epidemiology and Transmission

Curious about the science of COVID-19? In partnership with the Loudoun County Public Library, Janelia is hosting a virtual lecture series with Angela Rasmussen, a virologist at Columbia University. Watch the first two talks in the series here!

https://www.youtube.com/watch?v=6NhS6iurXkc&feature=youtu.be

https://www.youtube.com/watch?v=5ab4IiIGcpU&feature=youtu.be

Virologist Angela Rasmussen delivers a three-part series of virtual talks, “Demystifying COVID-19: The Science of SARS-CoV-2”. The Dialogues series is cohost...

03/16/2020

To limit exposure to #COVID19 and keep our employees safe, Janelia will reduce campus and research operations to a minimal level through March 31. We continue to monitor the situation and will update our status as more information becomes available.

03/06/2020

Fei Wang and Kaiyu Wang in Barry Dickson’s lab have mapped the neural circuits that link egg-laying to mating status in flies, making sure that female flies (like the array shown here) only lay eggs after mating.

“This is now perhaps one of the most completely understood behaviors in the fly,” says Dickson. “It's a great model for looking at how the brain integrates internal and external information.”

Their paper came out last week in Nature!
https://www.janelia.org/news/female-flies-only-lay-eggs-after-mating-heres-why

02/06/2020

We're thrilled to welcome Ron Vale, who officially took the helm as Janelia's new executive director earlier this week!

Virtual reality is helping scientists study how fruit flies use visual cues to refine their sense of direction. Read mor...
11/20/2019
To Navigate, Flies Make Flexible Mental Maps of the World | Janelia Research Campus

Virtual reality is helping scientists study how fruit flies use visual cues to refine their sense of direction. Read more in two new studies published today in Nature, from labs of Janelia’s Vivek Jayaraman and HHMI Investigator Rachel Wilson.

Flies use visual cues to finesse their mental maps of the environment. Two new studies use virtual reality to show how.

Congratulations to Janelian Igor Siwanowicz, who has won second place in the 2019 Nikon Small World competition for this...
10/22/2019

Congratulations to Janelian Igor Siwanowicz, who has won second place in the 2019 Nikon Small World competition for this photograph of freshwater protozoans called stentors.

Stentors, also known as trumpet animalcules, are shape-shifters, morphing from a horn shape into the pear shape shown here when swimming freely. They’re studied for their amazing regenerative abilities. A tiny piece of this two-millimeter single-celled animal, containing just a fragment of the multi-part nucleus (the colorful globular structures), can regrow into a new animal.

Stentors are a challenge to photograph. The chemicals used to prepare samples for a shot under a microscope can cause sensitive stentors to “collapse into a ball of protoplasm,” Siwanowicz says. But buried in an old paper, he found a reference to a technique for “relaxing” the stentors with magnesium ions — like “a bath in Epsom salt.” Using that trick, he’s captured them under a fluorescent microscope.

https://www.nikonsmallworld.com/galleries/2019-photomicrography-competition/depth-color-coded-projections-of-three-stentors-single-cell-freshwater-protozoans

The MouseLight Project Team has traced more than 1,000 neurons in the mouse brain. Their paper on this milestone is publ...
09/05/2019
MouseLight Project Team Maps 1,000 Neurons (and Counting) in the Mouse Brain | Janelia Research Campus

The MouseLight Project Team has traced more than 1,000 neurons in the mouse brain. Their paper on this milestone is published today in Cell. Check out the story and video! https://www.janelia.org/news/mouselight-project-team-maps-1000-neurons-and-counting-in-the-mouse-brain

Janelia Research Campus scientists have mapped more than 1,000 neurons in the mouse brain. It’s the most extensive neural wiring diagram available, and the data are accessible online. Scientists are batting a thousand in a project to reconstruct the mouse brain’s wiring diagram.

A new two-photon microscope breaks speed limits by compressing data. It can capture neurotransmitter release at hundreds...
07/31/2019
SLAP Microscopy Smashes Speed Barriers | Janelia Research Campus

A new two-photon microscope breaks speed limits by compressing data. It can capture neurotransmitter release at hundreds of synapses simultaneously! Check out the latest work from the Podgorski Lab, published this week in Nature Methods.

A new two-photon microscope captures videos of the brain faster than ever, revealing voltage changes and neurotransmitter release.

07/04/2019
ActinMito_short_v1.mp4

Happy #FourthofJuly to everyone in the United States! John Heddleston from Janelia’s Advanced Imaging Center captured these fireworks on the lattice light sheet microscope alongside AIC visitor Andy Moore. Video: dividing cells (actin and mitochondria are stained, color map: red, white, and blue).

Glia aren’t just support cells for neurons. New research from the Ahrens Lab shows that glia can perform computations th...
06/20/2019
Frustrated Fish Give Up Thanks to Glia, Not Just Neurons | Janelia Research Campus

Glia aren’t just support cells for neurons. New research from the Ahrens Lab shows that glia can perform computations that tell frustrated fish when to give up.

Giving up when efforts are futile depends on glial cells called radial astrocytes, highlighting a novel computational role for the underappreciated brain cells. Secured in place in a virtual-reality-equipped chamber, frustrated zebrafish just didn’t want to swim anymore. They had been “swimming...

To a fruit fly, the looming shadow of a predator looks a lot like an approaching landing place—but requires a different ...
06/11/2019
Flight or Alight? New Research Untangles How Flies Determine the Appropriate Response to a Looming Stimulus | Janelia Research Campus

To a fruit fly, the looming shadow of a predator looks a lot like an approaching landing place—but requires a different response. New research from Gwyneth Card's lab published in @natureneuro shows how flies react correctly based on context cues.

Two types of neurons in the fly brain help a fly land when it detects a looming stimulus – but only if it’s already in flight.

NeuroSeq, a Janelia Project Team, analyzed RNA from more than 200 populations of neurons. A paper describing the project...
06/10/2019
NeuroSeq Project Team Creates Atlas of Mouse Neurons | Janelia Research Campus

NeuroSeq, a Janelia Project Team, analyzed RNA from more than 200 populations of neurons. A paper describing the project is out now: https://www.janelia.org/news/neuroseq-project-team-creates-atlas-of-mouse-neurons

A Janelia project to profile different populations of mouse neurons yields insights into what sets brain cells apart. Sacha Nelson wanted to understand what sets different types of neurons apart.

Learn from Janelians Kristin Branson, Srini Turaga, and Larissa Heinrichs in the Society for Neuroscience virtual confer...
06/06/2019

Learn from Janelians Kristin Branson, Srini Turaga, and Larissa Heinrichs in the Society for Neuroscience virtual conference on machine learning on June 26: bit.ly/2H8zXnh

Thanks to everyone who submitted applications to our competition to decide Janelia’s next research area. We are no longe...
06/04/2019
Dates & Process | Janelia Research Campus

Thanks to everyone who submitted applications to our competition to decide Janelia’s next research area. We are no longer accepting pre-proposals. Stay tuned for updates!

HHMI is hosting an open, international competition to decide Janelia’s next research area. We are looking for a big idea that addresses a major unsolved problem in the life sciences, and a scientist to lead it.

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